A man presenting with tremors, sweating, and postural hypotension is most likely to have which condition?

The presence of tremors, sweating, and postural hypotension in this scenario strongly points toward pheochromocytoma. This condition involves tumors of the adrenal glands that produce excess catecholamines, such as epinephrine and norepinephrine. These hormones are responsible for the classic symptoms exhibited by the patient.

Tremors and sweating can occur due to the increased adrenergic activity caused by high levels of these catecholamines, leading to overstimulation of the sympathetic nervous system. Postural hypotension can result from the significant fluctuations in blood pressure that occur with catecholamine surges. When the patient stands, the blood vessels may not constrict effectively, leading to a drop in blood pressure, which explains the postural hypotension.

In contrast, while hyperthyroidism could contribute to tremors and sweating due to increased metabolism, it typically does not cause postural hypotension. Panic attacks may include tremors and sweating as part of their symptomatology, but they are unlikely to produce significant postural hypotension or the other classical signs associated with pheochromocytoma. Essential hypertension consistently raises blood pressure and does not correlate with the presented symptoms of sweating and tremors. Thus, pheochromocytoma is the most fitting