What follow-up investigation is appropriate for an 8-year-old boy with resolved glycosuria after an injury?

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In this scenario, an 8-year-old boy has experienced resolved glycosuria, which is the presence of glucose in the urine, potentially indicating issues with glucose metabolism. The follow-up investigation that is appropriate in this context is fasting blood glucose.

Fasting blood glucose is a critical test to assess the patient's baseline blood sugar level after a period of fasting (usually 8 hours or more). This test can help identify any underlying glucose regulation issues, such as diabetes mellitus, which could lead to glycosuria. Since the boy had an injury that may have temporarily affected his metabolic state, measuring fasting blood glucose can provide reassurance that his glucose levels are now normal, thus confirming that the glycosuria was likely not due to a chronic condition.

While other tests like glycated hemoglobin (HbA1c) provide average blood sugar levels over a longer period and random blood glucose tests assess current levels without fasting, they may not give the immediate insight needed after a resolution of symptoms. A 24-hour urine cortisol test is generally utilized to evaluate conditions related to cortisol overproduction, such as Cushing's syndrome, and is not directly relevant in this situation.

Conducting a fasting blood glucose test is straightforward and effective in determining whether there are any ongoing issues

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