Which hormones are secreted by the hypothalamus that directly affect the anterior pituitary?

Study for the PLAB Endocrinology Test. Prepare with flashcards and multiple-choice questions, each with hints and explanations. Get ready for your exam!

The hormones secreted by the hypothalamus that directly impact the anterior pituitary are indeed Gonadotropin-releasing hormone (GnRH) and Thyrotropin-releasing hormone (TRH). GnRH stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary, which are crucial for reproductive function. TRH prompts the anterior pituitary to release thyroid-stimulating hormone (TSH), which in turn regulates thyroid hormone production from the thyroid gland.

The function of these hypothalamic hormones is essential in the feedback regulation of the endocrine system. By promoting the release of key pituitary hormones, they play a significant role in various bodily processes, including growth, metabolism, and reproductive functions.

The other options include hormones that do not have a direct role in stimulating the anterior pituitary. For instance, insulin and glucagon are produced by the pancreas and primarily function in glucose metabolism rather than directly influencing the anterior pituitary. Growth hormone and prolactin, while significant hormones in the body, are secreted by the anterior pituitary itself and are not hypothalamic products. Lastly, while corticotropin-releasing hormone (CRH) does

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